| 中文名稱 | 努比亞山羊的神經性蠟樣脂褐質沈著症 |
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| 英文名稱 | Neuronal ceroid lipofuscinosis in nubian goats |
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| 建立日期 | 2007/11/01 |
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| 更新日期 | 2007/11/01 |
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| 中文描述 | 有蠟樣脂褐質沈著症的努比亞山羊會發展出神經功能障礙.症狀早在4月齡即發生,平均發病期在6月齡.所有病歷中都會導致死亡,即使有些動物在惡化後的改善時期會不一樣.沒有動物可活超過4歲.為一隱性遺傳疾病.屍解時可看到因為蠟樣脂褐質沈著造成的神經元腫大.無法治療.患有此病的母的動物有臉部粗操的傾向缺少女性特徵. |
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| 英文描述 | Nubian goats with neuronal ceroid-lipofuscinosis developed neurologic dysfunction. Signs started as early as 4 months of age, with an average age of onset of 6 months. In all cases there was progression leading to death, although in some animals there were varying periods of remission followed by exacerbation. No animal survived past 4 years of age. This is apparently inherited as an autosomal recessive. At necropsy there was swelling of neurons due to accumulation of ceroid-lipofuscin within neuronal cytoplasm. There is no treatment. There is a tendency for females with this disease to develop coarse facial features lacking feminine characteristics. |
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