| 英文描述 | Common; affects cerebral and cerebellar cortices. Most polioencephalomalacia is believed to be due to thiamine depletion. A form of this disease due to sulfur toxicity has also been described and diets based on molasses and urea are causes as well. A diet of BRASSICA OLERACEA, which has a high sulfur content, was associated with an outbreak of polioencephalomalacia in New Zealand. Signs occasionally asymmetrical. Red blood cell transketolase levels may be low, and blood thiamine levels are low. Both young and adults affected. Onset may be acute or gradual over one week or so. Afebrile unless convulsing. |