| 中文名稱 | 反芻獸及馬匹瘋草，黃蓍Astragalus，馬氏棘豆Oxytropis中毒 |
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| 英文名稱 | Locoweed, astragalus, oxytropis poisoning in ruminants and horses |
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| 建立日期 | 2007/11/01 |
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| 更新日期 | 2007/11/01 |
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| 中文描述 | 食用瘋草(棘豆屬或北耆屬種)會由於組織空泡化導致病狀,包括神經系統.中毒本源是苦馬豆素,會導致寡聚醣在溶體內累積,產生損傷類似於那些遺傳甘露糖過多症.瘋草是其中最有毀壞性的變且代價高的含毒植物對於美國西部的家畜食品.毒素累積性的;溫和案例一般解決於停止食用這些植物後一兩週內,但恢復慢性的瘋草病的病患不會出現.藉由病史和組織學診斷.一高量的瘋草於飲食中在症狀發生前需要一些月份後開始.動物可以獲得分辨這種植物的能力.除此之外會直接影響,一流產症候群和先天生硬或四肢畸形狀態屈伸類型已經報導於馬的後代和反芻獸其中有食用瘋草者. |
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| 英文描述 | Consumption of locoweed (OXYTROPIS or ASTRAGALUS spp.) causes signs due to vacuolation of tissues, including the nervous system. The toxic principle is swainsonine, which causes accumulation of oligosaccharides in lysosomes, producing lesions similar to those of heritable mannosidosis. Locoweeds are among the most destructive and costly poisonous plant to livestock production in the Western United States. The toxin is cumulative; mild cases generally resolve within 1-2 weeks of stopping consumption of the plants, but in patients with chronic locoism recovery does not occur. Dx by history and histology. A high level of locoweed in the diet is required for a few months before signs begin. Animals can acquire a taste for the plant. In addition to direct affects, a syndrome of abortion and congenital angular or flexion-extension type of limb deformities has been reported in the offspring of horses and ruminants consuming locoweed. |
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