| 英文描述 | In 1980 and 1981 many Japanese Black calves suffering from congenital lethal skin defects were seen in Kagoshima Japan. Calves were normal in size at birth but weak. Some were unable to stand or nurse at birth, but improved with nursing care. The hair was short, bristly and kinky. The skin was thick and hung in folds around the neck, belly, and joints. There was progressive generalized alopecia. There was progressive debility, and most were dead or killed within one month of birth. There was also ocular involvement, with progressive corneal clouding at birth or one week of age, followed by severe ocular infection. Histology showed a very thin epithelium, decreased or absent hair follicles, and increased and enlarged sweat glands. This may be inherited as an autosomal recessive. |
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