| 英文描述 | A progressive myeloencephalopathy has been reported in Brown Swiss and in crossbred Brown Swiss, as well as the red Angler breed, which had Brown Swiss cattle in its ancestry. Ataxia of the hind legs is first noted at 5-8 months and animals are unable to rise after 18-32 months. There are: 1. onset of bilateral hind leg weakness and ataxia; 2. deficient proprioceptive reflexes, normal motor and sensory reflexes, and no other clinically detectable neurologic abnormality; 3. no clinically significant skeletal or muscular abnormality; and 4. familial relationship to other affected animals. Familial, and probably inherited; in Brown Swiss it appears that a chromosome segment with major effect on yield is tightly linked to the weaver trait. Histopathology shows white matter lesions in the spinal cord, brainstem nuclei and cerebellar cortex. |