犬隻、牛隻及貓拉福拉病,腦細胞內包涵物

中文名稱犬隻、牛隻及貓拉福拉病,腦細胞內包涵物
英文名稱Lafora's disease, intraneuronal inclusions in dogs, cattle, and cats
建立日期2007/11/01
更新日期2007/11/01
中文描述神經細胞內含物來自多葡萄聚糖的沈澱,類似人類拉福拉病病患神經元出現的拉福拉體,曾被發現於沒有神經症狀的老年犬隻,且伴隨犬隻漸進性肌抽躍癲癇或頭,頸,和四肢的痙攣。極少數牛隻有臨床症狀和病理組織學發現確定是拉福拉病。拉福拉體在貓與神經疾病有關。症狀是漸進性的,沒有發現治療的方法。
英文描述Intraneuronal bodies caused by deposits of polyglucosans resembling Lafora bodies in neurons of people with Lafora's disease have been seen in aged dogs with no neurologic signs, and have also been associated with signs of progressive myoclonic epilepsy or head, neck, and limbs spasms in dogs. Cows with clinical signs and histopathological findings consistent with Lafora's disease have been described in rare cases. Lafora bodies were associated with neurologic disease in a cat. Signs are progressive, and no treatment has been described.

疾病類型

動物種類

關鍵詞

疾病症狀

【循環系】
  • 辨距不良, 延展過度, 延展不足
【皮膚系】
  • 叩診下陷或凹下去的地方回覆遲鈍
【肌骨系】
  • 共濟失調, 共濟不能, 蹣跚, 跌絆
  • 前肢痙攣, 肌陣攣
  • 頭, 臉, 頸部痙攣, 肌陣攣
【神經系】
  • 震顫, 發抖, 肌纖維自發性收縮, 寒顫
【其他】
  • 震顫,顫抖
  • 癲癇發作或暈厥, 痙攣, 突然發作, 虛脫