| 中文名稱 | 威瑪犬胸腺伴隨生長激素多重異常 |
| 英文名稱 | Thymic and growth hormone abnormalitis in weimaraners |
| 建立日期 | 2007/11/01 |
| 更新日期 | 2007/11/01 |
| 中文描述 | 一種妨礙發展和破壞的綜合症被在一群天生的威瑪犬裡報告。 受到影響的小狗有缺乏胸腺皮質部的胸腺。 一些小狗發展持久的傳染病,包括皮膚病,肺炎和消化的紊亂。 儘管經過治療,影響的小狗還是死亡。 可能是透過淋巴細胞的對植物血凝素的微弱的回應, 並且同時發生在生長激素新陳代謝過程異常的一種跡象, 在注射clonidine HCL之後, 能引起低於正常的發展激素的增加。 |
| 英文描述 | A syndrome of retarded growth and wasting was reported in a group of inbred Weimaraner dogs. Affected pups had a small thymus gland with absence of thymic cortex. Some of the pups developed persistent infections, including skin disease, pneumonia and digestive disorders. Most affected pups die despite conventional therapy. There may be a depressed response to phytohemagglutinin by lymphocytes, and a concurrent abnormality in growth hormone metabolism can cause a subnormal increase in growth hormone after the injection of clonidine HCL. |