| 中文名稱 | 德國牧羊犬的足墊之膠原蛋白異常 |
| 英文名稱 | Collagen disorder of the footpads of german shepherd dogs |
| 建立日期 | 2007/11/01 |
| 更新日期 | 2007/11/01 |
| 中文描述 | 在幾個星期到幾個月年齡, 德國牧羊狗也許發育較軟腳掌。 腕骨和掌骨是在高風險期, 潰瘍會顯現在受影響的腳掌墊。 遺棄的多條狗通常是會受影響的。 膠質分解和主要地神經炎症看在組織學。 治療是不成功的, 但自發退化通常在1 歲以前。 在2-3 歲以前許多受影響的狗死於腎臟澱粉變性病 。 |
| 英文描述 | At a few weeks to a few months of age, German shepherd dogs may develop soft and tender footpads. Carpal and tarsal pads are at high risk, and ulcers develop on affected pads. Multiple dogs of a litter are usually affected. Collagenolysis and predominantly neutrophilic inflammation are seen on histology. Treatment has been unsuccessful, but spontaneous regression by 1 year of age is common. By 2-3 years of age many affected dogs have died of renal amyloidosis. |