德國牧羊犬的遺傳性血小板促凝劑活性缺乏

中文名稱德國牧羊犬的遺傳性血小板促凝劑活性缺乏
英文名稱Hereditary lack of platelet procoagulant activity in german shepherds
建立日期2007/11/01
更新日期2007/11/01
中文描述一群有血緣關係的德國牧羊犬發生凝血方面的疾病,臨床症狀包括手術後出血,流鼻血,眼前房積血和血腫。患病的犬隻會發生輕微或中度的出血情形,但試管中的凝血作用卻正常,測試血小板的黏附性,凝集和分泌反應也正常。但是所有血小板促凝劑活性都不正常。這種犬隻疾病特徵近似人類的Scott症候群,是一種純合隱性遺傳。
英文描述German Shepherd dogs from a breeding colony developed bleeding disorders with clinical signs that included post-surgical hemorrhage, epistaxis, hyphema, and hematomas. The affected dogs experienced a mild to moderate bleeding tendency but had normal in vitro coagulation and normal response to tests of platelet adhesion, aggregation, and secretion. In contrast, abnormal values were consistently found in all tests of platelet procoagulant activity. This canine condition had features comparable to Scott syndrome of human beings and appears to be inherited as a homzygous recessive.

疾病類型

動物種類

關鍵詞

疾病症狀

【呼吸系】
  • 流鼻血, 鼻血, 鼻出血, 流血
【皮膚系】
  • 軀體任何部位之出血或凝血障礙, 流血
  • 淤血點, 淤血斑, 挫傷, 斑狀出血
  • 皮膚或皮下組織腫脹, 團塊, 腫塊, 結節
【感官系】
  • 眼前房積血, 黑眼