| 英文描述 | A vacuolar degeneration affecting primarily the gray matter in the central nervous system (CNS) has been described in young Australian Cattle Dogs. An initial presentation of seizures was followed by a progressive spastic tetraparesis. Grossly evident bilateral and symmetrical foci of malacia were in the nuclei of the cerebellum and brain stem and the gray matter of the spinal cord. Microscopically there was vacuolation of glial cells, dilation of the myelin sheaths and reactive astrocytosi. An inherited biochemical defect, possibly mitochondrial, has been proposed as the cause. |
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