| 英文描述 | A lethal hereditary syndrome of collies associated with several abnormalities: abnormal grey-silver hair pigmentation; cyclic depression of circulating neutrophils; bilteral scleral ocular ectasia; enteropathy; and gonadal hypoplasia. Cyclic neutropenic episodes occur at 11-12-day intervals and neutropenia lasts for an average of 3 days. Pups usually die within a few days of birth, and those that survive are overly susceptible to bacterial and fungal infections, rarely living past 3 months of age. Dx by breed, signs, determination of cyclic neutropenia. The prognosis is poor, but treatments which might be tried were discussed by Guilford. |
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