| 中文名稱 | 牛頭（梗）幼犬之致命性肢端皮膚炎 |
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| 英文名稱 | Lethal acrodermatitis in bull terrier puppies |
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| 建立日期 | 2007/11/01 |
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| 更新日期 | 2007/11/01 |
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| 中文描述 | 牛頭（梗）幼犬之致命性肢端皮膚炎的特色是生長延遲,咀嚼失調,全身孔洞皮膚損害,尤其是眼睛和嘴巴.膿性指頭炎,爪子營養失調,皮膚角化過度,和支架分裂.慢性膿皮症,呼吸感染越來越敏感.行為改變像是在16周齡過度睡眠後具侵略性在早年.有白血球過多症,低活性的血清鹼性磷酸和 丙氨酸氨基轉移酶.通常有高膽固醇血症.靠隱性染色體遺傳.通常感染的小狗能活7個月. |
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| 英文描述 | Lethal acrodermatitis in Bull Terriers is characterized by growth retardation, disordered mastication and deglutition, skin lesions around all body orifices most prominantly the eyes and mouth, paronychia and dystrophy of the nails, and hyperkeratosis and cracking of the footpads. Chronic pyoderma, diarrhea, increased susceptibility to respiratory infections, and behavioral changes including aggression at an early age followed by excessive sleeping by 16 weeks of age have been seen in some cases. There are neutrophilia, low activities of serum alkaline phosphatase and alanine aminotransferase, and often hypercholesterolemia. Inherited as an autosomal recessive. Median survival time of affected pups is about 7 months. |
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