| 英文描述 | Canine herpesvirus 1 (CHV-1) causes neonatal mortality in puppies during the first few weeks of life; virus replication is aided by low body temperatures resulting in increased susceptibility of neonates. Infection can occur in utero (associated with abortions, stillbirths, and infertility); at birth; by contact with diseased litter mates or carrier dogs; or by inhalation or ingestion of infected material. Death occurs soon after clinical signs are seen in most affected newborn puppies. Ocular signs often seen by four days postinfection in survivors. In older puppies this infection is subclinical or causes mild rhinitis or pharyngitis. In adults causes nodules, hemorrhages, or papulovesicular lesions (which might become ulcerated and poxlike) on the vagina, penis, or prepuce; conjunctivitis can also occur. |
|---|