| 英文描述 | A syndrome of systemic illness associated with a persistent pupillary dilation has been seen in cats from 8 weeks up to 11 years of age. The cause is not known, but multiple members of a litter have been affected. The affected cats are not blind, but there is little or no pupillary response to light. The pupillary problem persists after systemic signs are gone. Pupillary dilation can be unilateral or asymmetrical. Most commonly associated signs in cats include megaesophagus, incontinence, bradycardia, and decreased tearing and dry mucous membranes. Dysautonomia also affects dogs, and appears to be increasing in prevalence; the most common presenting signs in dogs are vomiting, diarrhea, and anorexia. A depletion of neurons and a rise in non-neuronal cells in autonomic ganglia is associated with this disease. |
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