| 中文名稱 | 犬隻的腎上腺皮質功能亢進症,腎上腺皮質醇增多症,庫興氏症候群 |
| 英文名稱 | Hyperadrenocorticism, hypercortisolemia, cushing's syndrome in dogs |
| 建立日期 | 2007/11/01 |
| 更新日期 | 2007/11/01 |
| 中文描述 | 增加血漿中可體松的濃度導致庫興氏症候群,外源的注射或者內源產物glucocorticoids的結果。 內源產物通常起因於一個腦垂體瘤生產過度的ACTH而活化腎上腺皮質。 單側或者(很少)雙側腎上腺瘤形成是在15-20%的原因。 糖尿病mellitus,次發性膿皮症和皮膚鈣化可能被看見,並且肌強直症作為一種稀有的併發症,經常在比較老的狗裡被看見。 計算的層析X射線攝影法已經用來鑑定腎上機能失調的地方。 腦幹疾病的神經病學的症狀可能伴隨著大型腦垂體瘤。 |
| 英文描述 | Increased levels of plasma cortisol leading to signs of Cushing's syndrome are the result of either exogenous administration or endogenous production of glucocorticoids. Endogenous production usually results from a pituitary tumor producing excessive ACTH which acts on the adrenal cortex. Unilateral or (rarely) bilateral adrenocortical neoplasia is the underlying cause in 15-20% of cases. Diabetes mellitus, secondary pyoderma, and calcinosis cutis may be seen, and myotonia is seen as a rare complication, often in older dogs. Computed tomography has been used to identify the sites of adrenal dysfunction. Neurologic signs of brain stem disease might be seen with a large pituitary tumor. |