| 英文描述 | A selective cobalumin malabsorption with an autosomal recessive mode of inheritance occurs in giant schnauzer dogs. Signs begin at 3 months of age, and affected dogs fail to thrive. They have moderate nonregenerative anemia with anisocytosis, occasional megaloblasts, moderate poikilocytosis, and neutropenia. Serum B12 levels are low, and parenteral, but not oral, administration of B12 reverses the clinical syndrome. Colbalamin deficiency associated with erythroblastic anemia and methylmalonic aciduria is a hereditary condition in Border Collies and has been described in a beagle. |
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