| 中文名稱 | 胰島素瘤，胰島細胞腫瘤，犬貓胰島素過高 |
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| 英文名稱 | Insulinoma, islet cell tumor, hyperinsulinism, in dogs and cats |
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| 建立日期 | 2007/11/01 |
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| 更新日期 | 2007/11/01 |
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| 中文描述 | 起作用的胰的小島細胞瘤來自馬蹄形小島中beta細胞； 胰島素的生產過剩導致低血糖。在成熟的狗裡非常普遍； 在貓裡稀有。 大多數是可能轉移而來的腺癌。快速的血糖過低因為隨著葡萄糖服用而減輕神經病學跡象。胰島素瘤決定性的診斷需要高血糖因子容忍測試或者測定血清免疫反應胰島素含量是高的儘管是血糖過低。有與胰的小島細胞癌相關的狗的周遭神經病的報告， 並且在那些狗裡的周圍多神經病的跡象繼葡萄糖服用之後將不消失；這種綜合症是被稱為神經性副腫瘤多肌病症。 |
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| 英文描述 | Functional pancreatic islet cell tumors arise from beta cells in the islets of Langerhans; overproduction of insulin leads to hypoglycemia. Most common in mature dogs; rare in cats. Most are adenocarcinomas that might metastasize. There is fasting hypoglycemia with relief of neurologic signs following glucose administration. Definitive diagnosis of insulinoma requires a glucagon tolerance test or determination of serum immunoreactive insulin levels that are high despite the hypoglycemia. There are reports of peripheral neuropathy in dogs associated with pancreatic islet cell carcinoma, and signs of peripheral polyneuropathy in those dogs would not disappear following glucose administration; this syndrome is known as paraneoplastic polymyopathy. |
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