| 中文名稱 | 西藏獒犬的肥大性神經病變 |
|---|---|
| 英文名稱 | Hypertrophic neuropathy in tibetan mastiff dogs |
| 建立日期 | 2007/11/01 |
| 更新日期 | 2007/11/01 |
| 中文描述 | 西藏獒犬的肥大性神經病變是一種隱性基因突變，造成許旺細胞的功能缺損伴隨著週期性的髓鞘脫去再生。疾病一開始發生在七至十週的狗，可見虛弱低血壓和反射不足。出現症狀後的七至十天，動物無法站立，四至六週後又可站立。可由屍檢確診，沒有治療方法。 |
| 英文描述 | An autosomal recessive trait in Tibetan mastiff dogs causes defective Schwann cell function, with recurrent demyelination and remyelination. Onset of disease occurs from 7-10 weeks of age, and is characterized by weakness, hypotonia, and hyporeflexia. Animals became recumbent about 7-10 days after onset of signs, and some regained ability to stand but were weak at 4-6 weeks from onset. Dx confirmed at necropsy. There is no treatment. |