| 中文名稱 | 豬隻的卡巴得（CARBADOX），喹乙醇（OLAQUINDOX）中毒 |
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| 英文名稱 | Carbadox, olaquindox, toxicity in pigs |
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| 建立日期 | 2007/11/01 |
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| 更新日期 | 2018/11/01 |
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| 中文描述 | 卡巴得，化學名(methyl-3- (2-quinoxalinylmethylene) carbazate-N1, N4-dioxide) ，常被添加於豬飼料中，做為成長促進劑或治療豬赤痢(swine dysentery)。研究發現，給與豬隻每公斤150毫克以上的劑量時，就會產生症狀，而且只要單次意外給藥即可能引發場中豬隻的中毒。在德國則有喹乙醇（OLAQUINDOX）使用過量而中毒的報告，造成腎上腺外層球狀帶(zona glomerulosa)損傷，使得身體無法產生醛固酮，引發低血鈉與高血鉀，造成鈉鉀比變低。診斷方式以檢驗餵飼的食物中，是否有過量的毒物為主。 |
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| 英文描述 | Carbadox (methyl-3- (2-quinoxalinylmethylene) carbazate-N1, N4-dioxide) is frequently fed to pigs as a growth promotant and as a treatment for swine dystentery. Experimental carbadox toxicity has occurred at dose rates of 150 mg/kg of feed, and accidental overfeeding has led to toxicity in the field. Toxicity due to olaquindox overdosing was reported in Germany. There is destruction of the adrenal zona glomerulosa; the inability to produce aldosterone causes hyponatremia and hyperkalemia and a decreased sodium/potassium ratio (Power et al.). Dx by examination of the feed suspected of containing the overdose. |
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