得文捲毛貓維生素K依賴性多重因子凝血病

中文名稱得文捲毛貓維生素K依賴性多重因子凝血病
英文名稱Vitamin k-dependent multifactor coagulopathy in devon rex cats
建立日期2007/11/01
更新日期2007/11/01
中文描述血液因子II, VII, IX, 和 X是維生素K依賴性的凝集蛋白.一種發生在得文捲毛貓顯然的先天性凝血異常與上述那些因子有關因而導致流血的異常.凝血酶原時間和activated partial thromboplastin times都會延長.血小板和纖維蛋白原的數量都是正常的.口服維生素K(每天5-10mg)會使那些因子恢復正常.診斷藉由對凝血因子的分析和對治療的反應.患此病的動物應該先排除掉毒鼠藥中毒,肝病,和malassimilation.
英文描述Blood factors II, VII, IX, and X are referred to as the vitamin K-dependent coagulation proteins. An apparently inherited coagulopathy in Devon Rex cats was associated with marked reductions in those factors and with bleeding disorders. Prothrombin times and activated partial thromboplastin times were prolonged. Platelet counts and fibrinogen values were normal. Oral treatment with vitamin K1 (5-10 mg daily) resulted in normalization of clotting factors. Dx by clotting factor assay and response to treatment. Warfarin intoxication, hepatic disease, and fat malassimilation should be ruled out in affected animals.

疾病類型

動物種類

關鍵詞

疾病症狀

【皮膚系】
  • 叩診下陷或凹下去的地方回覆遲鈍
  • 軀體任何部位之出血或凝血障礙, 流血
  • 禽類之肉冠與(或)肉垂蒼白
  • 淤血點, 淤血斑, 挫傷, 斑狀出血
  • 皮膚或皮下組織腫脹, 團塊, 腫塊, 結節
【神經系】
  • 厭食症, 食慾喪失或減退, 不攝食, 停止進食
【感官系】
  • 結膜, 鞏膜充血, 血管異常分布
  • 結膜, 鞏膜, 發紅
【其他】
  • 猝死, 突發性死亡