| 中文名稱 | 得文捲毛貓維生素K依賴性多重因子凝血病 |
| 英文名稱 | Vitamin k-dependent multifactor coagulopathy in devon rex cats |
| 建立日期 | 2007/11/01 |
| 更新日期 | 2007/11/01 |
| 中文描述 | 血液因子II, VII, IX, 和 X是維生素K依賴性的凝集蛋白.一種發生在得文捲毛貓顯然的先天性凝血異常與上述那些因子有關因而導致流血的異常.凝血酶原時間和activated partial thromboplastin times都會延長.血小板和纖維蛋白原的數量都是正常的.口服維生素K(每天5-10mg)會使那些因子恢復正常.診斷藉由對凝血因子的分析和對治療的反應.患此病的動物應該先排除掉毒鼠藥中毒,肝病,和malassimilation. |
| 英文描述 | Blood factors II, VII, IX, and X are referred to as the vitamin K-dependent coagulation proteins. An apparently inherited coagulopathy in Devon Rex cats was associated with marked reductions in those factors and with bleeding disorders. Prothrombin times and activated partial thromboplastin times were prolonged. Platelet counts and fibrinogen values were normal. Oral treatment with vitamin K1 (5-10 mg daily) resulted in normalization of clotting factors. Dx by clotting factor assay and response to treatment. Warfarin intoxication, hepatic disease, and fat malassimilation should be ruled out in affected animals. |