| 中文名稱 | 犬貓中毒引起的上皮組織壞死病變 |
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| 英文名稱 | Toxic epidermal necrolysis in dogs and cats |
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| 建立日期 | 2007/11/01 |
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| 更新日期 | 2007/11/01 |
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| 中文描述 | 少見.有急性的多發性或全身性類天皰瘡和潰爛性皮膚炎病灶發作.病灶可能到處都是,但通常都與口腔黏膜和皮膚黏膜交界處有關.伴隨皮膚疼痛.通常會出現Nikolsky症狀.與藥物,毒物,感染,癌症,和其他系統異常有關.由組織學,理學和皮膚切片檢查診斷.完全的上皮組織凝固性壞死是組織病理學發現的特徵.病灶較嚴重,系統性症狀和與黏膜的關係比葡萄球菌性頭鱗癬皮膚症候群多.相信有一種免疫成分. |
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| 英文描述 | Rare. There is an an acute onset of multi-focal or generalized vesicobullous and ulcerative lesions. Lesions may be anywhere, but often involve the oral mucosa and mucocutaneous junctions. Accompanied by cutaneous pain. Nikolsky sign is usually present. Has been associated with drugs, toxins, infections, malignancies, and other systemic disorders. Dx is based on history, physical, and skin biopsy. Complete epidermal coagulation necrosis is a characteristic histopathologic finding. Lesions are more severe, systemic signs and mucosal involvement more evident than in staphylococcal scalded skin syndrome. Believed to have an immunologic component. |
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