| 英文描述 | Chronic renal disease or congenital renal anomalies resulting in severe renal impairment cause phosphorus retention and progressive hyperphosphatemia. Renal disease can decrease production of 1,25 dihydroxycholecalciferol with decreased intestinal calcium transport. Both mechanisms contribute to hypocalcemia and parathyroid stimulation. Signs relate to renal insufficiency and skeletal lesions of hyperparathyroidism. Dx is based on evidence of renal failure, skeletal demineralization, serum analysis of Ca, P, and alkline phosphatase. |
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