| 中文名稱 | 貓先天性的吡咯紫質沉著病（??病） |
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| 英文名稱 | Feline congenital porphyria |
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| 建立日期 | 2007/11/01 |
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| 更新日期 | 2007/11/01 |
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| 中文描述 | 少見.這是一種牽涉到生物合成血基質路徑的遺傳性疾病,特徵是血液,組織和排泄物中過量和不正常的紫值.可由正染色體顯性遺傳.暹羅貓和短毛家貓曾罹患過(Watson).一隻有前驅紫質症的貓,特徵為持續的delta aminolevulinic酸性尿,但是腎臟和尿液中的porphobilinogen濃度也顯示正常(Watson).貓有可能表現出光敏感性,腎臟疾病,或溶血性貧血.診斷可藉由徵兆,紫質分析,組織病理學的紫質色素表現,或持續的delta aminolevulinic酸性尿伴隨正常血鉛濃度.尿液或牙齒中的紫質在紫外光下會發出螢光. |
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| 英文描述 | Rare. This is an inherited disease involving the biosynthetic heme pathway, characterized by excessive amounts and abnormal types of porphyrins in blood, tissues, and excreta. Can be inherited as an autosomal dominant trait. Siamese cats and domestic shorthaired cats have been affected (Watson). A cat with precursor porphyria, characterized by persistent delta aminolevulinic aciduria but normal concentrations of porphobilinogen in urine and feces has also been described (Watson). Cats might show photosensitivity, renal disease, or hemolytic anemia. Dx by signs, porphyrin analyses, demonstration of porphyrin pigment on histopathology, or persistent delta aminolevulinic aciduria with normal blood lead levels. Porphyrins in urine or teeth fluoresce under ultraviolet light. |
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