貓的全身性淋巴腺病,擬似淋巴瘤

中文名稱貓的全身性淋巴腺病,擬似淋巴瘤
英文名稱Generalized lymphadenopathy resembling lymphoma in cats
建立日期2007/11/01
更新日期2018/11/01
中文描述曾有病例報告描述六隻貓咪(年齡1-4歲)發生體表淋巴節腫大,經過淋巴節採樣檢查,發現後述組織學特徵,並且於1-17週後自行消退。發現到的組織學特徵包括淋巴節血管豐富、初級與次級濾泡的生發中心活化、皮質與髓質竇充滿各種型態的細胞、沒有血管侵犯現象、也沒有高度惡性的腫瘤變化。此症狀被認為是一種免疫反應的結果。本病例中的5隻貓咪,貓白血病抗原檢查為陰性;但是六隻貓咪在進行腫瘤病毒相關的細胞膜抗原檢測時,呈現出32倍的抗體力價,而且其中兩隻中和抗體力價也大於10倍。貓愛滋病(慢病毒)目前也被認為可能與此疾病有關,且應該對患病貓咪進行是否感染貓愛滋病的檢查。
英文描述Six cats (1-4 years of age) were described which had enlargement of peripheral lymph nodes and lymph node biopsy results with many histologic features of lymphoma that regressed spontaneously within 1-17 weeks of diagnosis. Histologic features (in some cases) which did not indicate malig- nancy were abundant nodal vascularity, primary and secondary follicles with active germinal centers, mixed cells in the subcapsular or medullary sinuses, lack of capsular invasion, and lack of high-grade anaplastic changes. This syndrome was believed to be an immune response. The five cats that were tested were negative for FeLV antigen but 6 cats tested had FOCMA antibody titers of 1:32 and 2 had neutralizing antibody titers >1:10. Feline immundeficiency virus (Lentivirus) has recently been described, and should be considered when evaluating a cat with this syndrome.

疾病類型

動物種類

關鍵詞

疾病症狀

【其他】
  • 淋巴腺病; 淋巴結腫脹, 團塊, 肥大