| 中文名稱 | 小馬中毒引起的肝衰竭，鐵質中毒 |
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| 英文名稱 | Toxic hepatic failure, iron toxicity, in foals |
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| 建立日期 | 2007/11/01 |
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| 更新日期 | 2007/11/01 |
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| 中文描述 | 一有毒的肝衰竭症候群於二到五日齡大小馬已經被見到於美國許多區域.於驗屍時有標記門靜脈週邊纖維化以及膽管增生.在死亡前會有升高的酵素像是山梨醇脫氫酶,並且這些指出為活性肝病.這疾病被從小馬口服預防接種產生有'Primapaste', 包含鐵.一不可辨別的症候群被投與每公斤16毫克含鐵的反丁烯二酸到小馬而產生.小馬不應該接收鐵的供應於出生前三天(Mullaney和Brown).藉由歷史和驗屍檢查來診斷.肝鐵含量也許再驗屍檢查時會上升. |
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| 英文描述 | A syndrome of toxic hepatic failure in 2-5 day old foals has been seen in several regions of the U.S. At necropsy there was marked periportal fibrosis and biliary hyperplasia. There are elevations of enzymes such as sorbitol dehydrogenase prior to death, and these indicate active liver disease. The disease was reproduced by oral inoculation of foals with 'Primapaste', which contains iron. An indistinguishable syndrome has been produced by administration of 16 mg/kg ferrous fumarate to foals. Foals should not received iron supplementation in the first 3 days of life (Mullaney and Brown). Dx by history and necropsy. Liver iron levels may be elevated at necropsy. |
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