| 中文名稱 | 小馬選擇性免疫球蛋白IgM缺乏症 |
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| 英文名稱 | Selective igm deficiency in foals |
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| 建立日期 | 2007/11/01 |
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| 更新日期 | 2007/11/01 |
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| 中文描述 | 少或缺乏免疫球蛋白M導致增加對許多感染的敏感性,但通常呼吸道感染是來自許多變化不同的微生物.罕見.藉由證實缺乏或只含少量的免疫球蛋白M,有血清免疫球蛋白M濃度至少二SD,低於正常平均值.可見於許多種別.大部分普見,受影響小馬死於十歲齡前.一些被診斷於二到五歲齡,常常聯繫有淋巴肉瘤.沒有明確的治療方法.原因不明,但是基因基礎是被懷疑的. |
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| 英文描述 | Low or absent IgM leads to increased susceptibility to many infections, but usually infections of the respiratory tract from a variety of organisms. Rare. Dx by demonstrating absent or very low IgM, with serum IgM concentration at least 2 SD below the normal mean value. Seen in several breeds. Most commonly, affected foals die before 10 months of age. Some affected foals are stunted but respond temporarily to antibiotic therapy, with death or euthanasia by 1-2 years of age. Some are diagnosed at 2-5 years of age, often in conjunction with lymphosarcoma. There is no specific treatment. The cause is unknown, but a genetic basis is suspected. |
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