馬匹的免疫媒介多發性關節滑膜炎

中文名稱馬匹的免疫媒介多發性關節滑膜炎
英文名稱Immune-mediated polysynovitis in horses
建立日期2007/11/01
更新日期2007/11/01
中文描述四匹小馬被發現許多關節出現無菌發炎的現象。只有僵硬,沒有明顯的跛行,關節有擴大。患病的小馬1-3個月大。小馬沒有風濕病因子或抗核抗體力價,紅斑性狼瘡細胞也是陰性。滑液囊液分析顯示輕微的有核細胞增加(完整良好的嗜中性球)。組織學檢查關節囊液顯示有輕微的淋巴漿細胞滑膜炎,出現在關節滑膜上的免疫球蛋白在三匹小馬都有。所有病例的多關節滑膜炎都與關節外的其他地方感染有關。在使用糖類皮質素治療後有短暫的改善於其中一匹在原發性非關節感染後存活的小馬。類似的症候群有發生於馬匹的報告(Lumsden)。
英文描述Four foals were described which had sterile inflammation of many joints. There was stiffness only, with no overt lameness, and joints were distended. Affected foals were 1-3 months of age. Foals had no rheumatoid factor or antinuclear antibody titers, and lupus erythematosus cell preparations were negative. Synovial fluid analysis showed mild increases in nucleated cell count (predominantly well-preserved neutophils). Histologic examination of the synovium revealed mild lymphoplasmacytic synovitis, and the presence of immunoglobulin was verified in the synovial membrane of 3 foals. In all cases the polysynovitis was associated with an infection at a site other than the joints. Transient improvement with glucocorticoid treatment was reported in the one foal which survived the primary non-joint infection. A similar syndrome was reported in a horse (Lumsden).

疾病類型

動物種類

關鍵詞

疾病症狀

【一般】
  • 發燒, 發熱, 體溫過高
【皮膚系】
  • 叩診下陷或凹下去的地方回覆遲鈍
  • 皮膚水腫
【肌骨系】
  • 前腳疼痛, 前腳
  • 前肢跛足, 強直, 跛行
  • 前肢疼痛, 前腳
  • 前肢或上肢腫脹; 前肢或上肢在關節或非關節處之團塊
  • 全面性跛足或強直, 跛行
  • 後肢或下肢跛足, 強直, 跛行
  • 後肢或下肢腫脹; 後肢或上肢在關節或方關節處之團塊
【神經系】
  • 厭食症, 食慾喪失或減退, 不攝食, 停止進食